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The current review will focus on four main areas: (1) general description of oxidative stress markers in SLE, (2) alteration of redox state and complication of disease (3) role of redox mechanisms in the initiation and execution phases of apoptosis, and (4) intracellular glutathione and its checkpoints with lymphocyte apoptosis represent novel targets for pharmacological intervention in SLE
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As one of the earliest signs of aging, graying hair is widely attributed to a depletion of enzymes involved in melanogenesis (making color), impaired DNA repair, and weakened antioxidant mechanisms