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TB-500 is a synthetic peptide that replicates the active region of Thymosin Beta-4 (TB4), a naturally occurring 43-amino-acid protein

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Fully recovered short bowel syndrome provided finally defined physiological adaptive enlargement, adapted-to-normal tissue ratios, muscle thickness with a fourfold increase, villus height and crypt depth with a twofold increase, and, later, a discrepant decrease of the inner (circular) muscular layer, with all intestinal wall layers accordingly adapted [155]