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Consistent with this, exogenous α-KG supplementation can enhance Arg1 expression and suppress iNOS expression, and changes in metabolic ratios such as α-KG/succinate are closely associated with the activation of M2-related transcriptional programs ( It should be noted that the effects of Gln metabolism on polarization direction are markedly context-dependent
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Strenght:250mg
FDA PCAC July 2026 briefing document