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Similarly, endothelium-mediated vasodilator responses were restored when a transgene for GPx1 was introduced into the CBS +/− mice by crossbreeding transgenic GPx1 overexpressing mice and CBS deficient mice, suggesting that increased expression of GPx1 could compensate for the negative effects of homocysteine on bioactive NO [60]

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Vegetarians, vegans or people with an unbalanced diet can also experience a vitamin B12 deficiency

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