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Inflammatory Bowel Disease (IBD) and Colitis In models of ulcerative colitis and Crohn’s-like inflammation, BPC-157 reduced symptoms such as: Intestinal bleeding Epithelial erosion Immune cell infiltration Weight loss and diarrhea “BPC-157 therapy improved outcomes in acetic acid-induced colitis models, reducing oxidative stress and promoting mucosal regeneration.” — Tkalcevic, V