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To date, many cancer cell lines evaluated, including prostate, breast, bladder, colon, glioma, kidney, melanoma, and leukemia cells, along with fresh patient tumors cultured ex vivo , have been found to exhibit some degree of methionine dependence [1,13,14,17-19]
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Additionally, while some may tolerate a high amount of caffeine, many will experience side effects, including hormone changes and sleep disturbance