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All participants were counseled on lifestyle modification, including a daily 500-kcal calorie deficit and at least 150 minutes of physical activity per week
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In a second study, 18 hypertensive smokers whose blood pressures were not controlled with ACE inhibitor monotherapy (enalapril or captopril) were given adjunct treatment with NAC, 1.8 g/day for 21 days, resulting in a decrease in 24 h ambulatory and daytime systolic and diastolic blood pressures (39)