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Future Perspectives To sum up, it is generally believed that IGF1 enhances mitochondrial function by promoting both mitochondrial biogenesis and mitophagy under several conditions of metabolic or mitochondrial stress

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Eligibility Criteria Studies were eligible if they evaluated BPC-157, thymosin beta-4 or marketed derivatives (including TB-500), GHK-Cu, or other peptide-based agents commonly promoted for musculoskeletal healing or recovery and reported outcomes relevant to musculoskeletal pathology, orthopaedic surgery, postoperative recovery, or perioperative risk domains