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Studies from Sikiric's group have also reported interactions with dopaminergic and serotonergic systems in rodent models, which partly explains interest in CNS applications
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Glutathione is the essential co-factor or the product of several oxido-reductases, which link the NAD(P)H pool (that is produced by metabolic carbohydrate conversion to carbon dioxide), to the reduction of ROS generated by the electron flux of oxidative phosphorylation