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Injectable administration provides systemic distribution with higher bioavailability, reaching connective tissue, joints, and internal organs that topical application cannot access
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What the FDA still says about the safety of these peptides FDA's bulk substances page retains the reasoning it used in 2023 for BPC-157, GHK-Cu (injectable routes), TB-500 and Epitalon: the agency identified risks of immunogenicity, uncertainty about peptide-related impurities, and no meaningful human exposure data