Description
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During oxygenated or oxygen-deprived states, hypoxia-inducible factor 1 (HIF-1) promotes Th17 differentiation by directly transcriptionally activating RORγt and facilitating the formation of a tertiary complex comprising RORγt, p300, and HIF-1 at the IL-17 promoter region [41]
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[DOI] [PMC free article] [PubMed] [Google Scholar] [13].Stathopoulou C, Nikoleri D, Bertsias G