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effects on clinical pregnancy and live birth rates were less consistent across treatments, although testosterone supplementation showed a statistically significant live-birth improvement (odds ratio 2.19, 95% CI 1.11–4.32)

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Injection of mice with RELM-β induced insulin resistance (137) and transgenic mice over-expressing RELM-β in the liver exhibit hyperglycemia, hyperlipidemia, fatty liver, and pancreatic islet enlargement when fed a high fat diet but not when fed a normal diet (138)