Description
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A randomised controlled trial published in the Journal of Clinical and Aesthetic Dermatology showed measurable skin lightening after 4 weeks of glutathione supplementation
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To examine this notion, we prepared the linear α-conotoxin SI peptide by solid phase peptide synthesis (SPPS), with two Cys (3&13) protected with the trityl PG to afford the free S–H of these Cys residues after trifluoroacetic acid (TFA) cleavage, and two additionally modified Cys (2&7) with the (Acm) moiety, (Supplementary Fig