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In addition, the same study also showed that the treatment of erastin (an inducer of iron toxicity) decreased GPX4 and ferritin levels in human epidermal melanocytes (HEMs) while increasing TfR and Acyl-CoA synthetase long-chain family member 4 (ACSL4) expression, indicating that HEMs are sensitive to ferroptosis (97)
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Unfortunately, it has also made it easier to purchase products without understanding whether they’re appropriate, how they should be used, or whether the source can be trusted