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In fact, GSH is essential for some functions of the immune system, both innate and adaptive, including T-lymphocyte proliferation, 38 , 39 phagocytic activity of polymorphonuclear neutrophils (PMN), 40 and dendritic cell functions, 41 and is also important for the first step of adaptive immunity, consisting of the antigen presentation by antigen-presenting cells (APC)
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However, it would appear that a small amount of cobalamin can be synthesized by the intestinal flora present in an area unable to absorb it [2], therefore making the vitamin unavailable