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Partial reduction reactions occur even under physiologic conditions, causing release of superoxide radical (O 2 · ) and hydrogen peroxide.[] NATURAL SOURCES OF GLUTATHIONE Glutathione is available naturally in fresh leafy vegetables, broccoli, walnuts, chestnuts, oranges, whey protein, tomatoes, fresh fruits, avocados, asparagus, meat, and poultry.[] PHARMACEUTICAL FORMULATIONS OF GLUTATHIONE Glutathione is available as oral preparations (pills, sublingual tablets, solutions, syrups, and sprays) and parenteral forms (IV preparations)
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The development of new antifungal drugs for aspergillosis includes Re-zafungin (CD101-IV), a novel echinocandin with unique pharmacokinetic properties that allows for weekly dosing and shows effective in vitro and in vivo activity against multiple Aspergillus species (Sandison et al., 2017