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Previous studies suggest that the hierarchy of selenoprotein expression is dependent on sequences in the 3′ UTR of Sec-gene transcripts, as an exchange of 3′ UTRs (including the SECIS elements) among various selenoprotein mRNAs altered their translational efficiency in selenium-depleted cells (30)

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2015 Jul 7;4:321 Ahokas EK, Ihalainen JK, Hanstock HG, Savolainen E, Kyröläinen H